Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules

Aim: Differentiation of thyroid nodules, either as benign or malignant, is a real diagnostic challenge. Inflammation has an important role in development the malignancy. Therefore, inflammatory markers are associated with malignant nodules. Platelet /lymphocyte ratio (PLR) also one novel indices derived from hemogram tests. We hypothesized whether PLR was For this purpose, we compared levels patients nodules to subjects nodules. Methods: The who visited outpatient internal medicine clinics our institution diagnosis nodule were enrolled present retrospective study. According examination fine needle aspiration cytology (FNAC) specimen grouped into groups. groups compared. Results: Median values and 106 (48-432) % 119 (48-365) %, respectively (p=0.001). value higher than 106% 69% sensitivity 51% specificity detecting (AUC: 0.59, p=0.001, 95% CI: 0.54-0.65). positively correlated TSH level (r=0.10, p=0.34). Conclusion: suggest that elevated could be additional tool differentiate ones supportive sonography, scintigraphy cytology.